Where do I sign up?
If you're wondering what joint supplements contain collagen II, I have found *two: Grand Meadows Grand HA ($1.33/day, 1,000mg/oz) and Nimble Supreme ($1.58/day, 600mg/oz). Problem is, I already use glucosamine/chondroitin supplements, Absorbine FlexMax ($1.39/day) and Smartflex Senior ($1.13/day). I don't need yet another one, and I don't want to switch to something I haven't tested out.
Looking high and low...
I looked around for a cheap source of pure collagen in the hopes that it would:
- cost less
- let me control dosage (like I'm such an expert, right?)
The Journal of Veterinary Pharmacology and Therapeutics study showed good results for horses getting 320, 480, or 640 mg/day -- with 480 being the optimal dose. The Supplement Direct collagen contains 100 grams. My math skills are pretty poor but I think with a 480-500mg dosage that's 15 cents/day. The bag even comes with a 250mg scoop -- what more could I ask for?
*Another brand with type II collagen is Actiflex -- 3,000 mg/oz? Has anyone ever used it?
Update: from questions posed in comments...
Questions and answers
What's the difference between active type II collagen and inactive collagen?
When you're talking about undenatured collagen, you expect about 25% of the weight in milligrams to be "active" (which I think means absorbable). A 320mg dose of type II collagen would have about 80 active mgs.
What is undenatured collagen vs. denatured collagen?
Denatured, or hydrolized collagen has been processed with high heat and/or chemicals. These processes alter the molecular structure of the protein, rendering the it ineffective as an immunomodulator. There are no peer-reviewed scientific studies showing that denatured type II collagen provides any joint health benefits.
Undenatured type II collagen is made using little or no heat and very limited processing - just enough to concentrate the collagen and make it soluble. The UC·II manufacturing process ensures that the collagen remains biologically active in its most native, triple helix form, with its immunomodulating ability intact.
How do I know the collagen I buy has the active ingredients and formulation that will help me or my horse?
Suprise! You DON'T. Welcome to the unregulated world of supplements. Unless the manufacturer voluntarily submits samples to Consumer Labs or the NASC, you can't really be certain what you're getting. And if you read Consumer Reports nutraceutical reports, you'll be dismayed to see that paying a lot of money is far from being a guarantee of quality. In some cases dollar store brands outperformed products sold at 4-5 times the price!